Although home remedies cannot cure sinus infection, people can use them to lessen their discomfort. Steam inhalations are the best way to work directly on the membranes, loosening thick mucus and fighting infection. Inhaling steam from a vaporizer or a hot cup of water can soothe inflamed sinus cavities. Another treatment is saline nasal spray, which can be purchased in a pharmacy. A hot water bottle, hot, wet compresses, or an electric heating pad applied over the inflamed area also can be comforting.